Calcium D-Glucarate
Detox · hormone clearance
Calcium D-Glucarate: Detox · hormone clearance. A compound that supports the body's natural clearance of excess hormones and toxins through the liver's glucuronidation pathway. Standard dose 500-1,000 mg, taken in the morning, about $18/month. Evidence rating: moderate evidence.
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What is Calcium D-Glucarate?
Calcium D-glucarate is the calcium salt of D-glucaric acid, a substance found in fruits and vegetables. In the body it slows an enzyme (beta-glucuronidase) that would otherwise recycle substances the liver has tagged for removal, which in theory supports clearance of excess estrogen and certain waste products through the glucuronidation detox pathway. The concept is well described in laboratory and animal work, while direct human outcome trials are still limited, so it is best framed as a supportive, emerging option rather than proven. Because it can speed the clearance of some drugs, anyone on prescription medication should check with a clinician or pharmacist. Typical use is 500 to 1000 mg daily.
A compound that supports the body's natural clearance of excess hormones and toxins through the liver's glucuronidation pathway.
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