Home/Ingredients/Cat's Claw (Uncaria tomentosa)
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Cat's Claw (Uncaria tomentosa)

Immune · joint comfort

MODERATE EVIDENCEVEGANREAD THE RESEARCH18 CLINICAL STUDIES
Written to our editorial standards · reviewed against published research· Updated 5 Jun 2026
Last reviewed: May 30, 2026
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Cat's Claw: Immune · joint comfort. A Peruvian vine bark used traditionally for immune support and joint comfort. Standard dose 350-500 mg, taken in the morning, about $11/month. Evidence rating: moderate evidence.

Where to buy

NOWFOODSCat's Claw100 VEG CAPSDIETARY SUPP.
RECOMMENDED
NOW Foods, Cat's Claw
350-500 mg · Morning · ~$11/month

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All product options

NOWFOODSCat's Claw100 VEG CAPSDIETARY SUPP.BESTSELLER
Cat's Claw
NOW Foods
100 veg caps · $11 · ★ 4.7
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NATURE'SWAYCat's Claw100 CAPSULESDIETARY SUPP.BEST VALUE
Cat's Claw
Nature's Way
100 capsules · $12 · ★ 4.6
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SOLARAYCat's Claw100 VEG CAPSDIETARY SUPP.PREMIUM
Cat's Claw
Solaray
100 veg caps · $13 · ★ 4.5
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SOURCENATURALSCat's Claw120 TABLETSDIETARY SUPP.PREMIUM
Cat's Claw
Source Naturals
120 tablets · $15 · ★ 4.5
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What is Cat's Claw?

Cat's claw (Uncaria tomentosa) is a woody vine from the Amazon, named for its claw-shaped thorns, whose bark has been used traditionally for immune support and joint comfort. Its oxindole alkaloids and other compounds show anti-inflammatory and immune-modulating activity in laboratory studies, and small human trials report improvements in joint tenderness in osteoarthritis and rheumatoid conditions. Because it modulates the immune system, people with autoimmune conditions or on immunosuppressants should be cautious and check with a clinician, and it has mild blood-thinning activity. Look for an extract standardized to oxindole alkaloids and low in tannins, typically 350 to 500 mg daily.

WHY IT MATTERS

A Peruvian vine bark used traditionally for immune support and joint comfort.

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Common questions

What is Cat's Claw?
Cat's claw (Uncaria tomentosa) is a woody vine from the Amazon, named for its claw-shaped thorns, whose bark has been used traditionally for immune support and joint comfort. Its oxindole alkaloids and other compounds show anti-inflammatory and immune-modulating activity in laboratory studies, and small human trials report improvements in joint tenderness in osteoarthritis and rheumatoid conditions. Because it modulates the immune system, people with autoimmune conditions or on immunosuppressants should be cautious and check with a clinician, and it has mild blood-thinning activity. Look for an extract standardized to oxindole alkaloids and low in tannins, typically 350 to 500 mg daily.
What is Cat's Claw used for?
Immune · joint comfort. A Peruvian vine bark used traditionally for immune support and joint comfort.
What is the standard dose of Cat's Claw?
350-500 mg, typically taken in the morning. Approximate cost is $11 per month.
Who should avoid Cat's Claw?
Use extra caution, and speak to a clinician first, if you are autoimmune condition, on blood thinners.
How strong is the evidence for Cat's Claw?
Moderate evidence for its primary uses. See the full study list on the research page.

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