Curcumin is the active polyphenol in turmeric. Raw curcumin has poor bioavailability, the studied effects rely on enhanced forms (BioPerine, Meriva phytosome, Theracurmin).
Curcumin produced pain reductions comparable to ibuprofen and diclofenac in knee osteoarthritis, with significantly fewer adverse events.
Curcumin showed significant antidepressant effects vs placebo (SMD -0.34). The effect was larger in middle-aged adults and as adjunct to antidepressants.
Curcumin significantly reduced circulating IL-6, hs-CRP, and TNF-α, major inflammatory markers, across multiple conditions.
We prioritize randomised controlled trials and meta-analyses over single observational studies. Animal and in-vitro data are listed as "mechanistic", they suggest direction, not human effect size.
We don't cherry-pick favourable studies, omit conflicting evidence, or cite industry-funded trials without flagging the conflict of interest where known.
The research is one thing, what to take, at what dose, paired with what, is another. We compose stacks that turn the evidence into a daily routine.
Studies referenced are real published research. Summaries are paraphrased for accessibility, for exact methods and full text, click through to PubMed. Educational use only, not medical advice. Consult a qualified clinician before starting any new supplement.