Ingredients · L-Theanine · Research
Clinical research

What does the research say about L-Theanine?

strong evidence

L-theanine is the unique amino acid in tea that promotes alpha brain waves, the 'calm focus' state. It works fast (30-60 minutes) and pairs particularly well with caffeine.

Best-evidenced use cases
  • Reducing caffeine jitters and anxiety
  • Sustained focus during cognitive work
  • Pre-stress events (presentations, exams)
  • Mild evening relaxation without sedation
  • Acute anxiety management

4 key studies

Search PubMed for more
  • 01RCT2008Nutritional Neuroscience

    L-theanine and caffeine on cognitive performance and mood

    Owen et al.
    Sample
    27 healthy adults
    Dose
    97 mg theanine + 40 mg caffeine
    Duration
    Single dose
    Key finding

    The combination improved accuracy on attention-switching tasks and reduced susceptibility to distractor stimuli vs caffeine alone, the canonical 'calm focus' finding.

    Read on PubMed
  • 02RCT2007Biological Psychology

    L-theanine and stress response

    Kimura et al.
    Sample
    12 healthy adults
    Dose
    200 mg theanine
    Duration
    Single dose, acute stressor
    Key finding

    L-theanine reduced heart rate and salivary IgA responses to acute stress, suggesting attenuation of sympathetic nervous system arousal.

    Read on PubMed
  • 03Systematic Review2020Plant Foods for Human Nutrition

    Anti-stress effects of L-theanine: meta-analysis

    Williams et al.
    Sample
    9 RCTs
    Dose
    200-400 mg/day
    Duration
    Single dose to 8 weeks
    Key finding

    L-theanine significantly reduced acute stress and anxiety in adults exposed to stressors. Chronic supplementation effects were smaller but consistent.

    Read on PubMed
  • 04RCT2011Journal of Functional Foods

    Effects of L-theanine on attention and reaction time

    Higashiyama et al.
    Sample
    18 attention-prone adults
    Dose
    200 mg theanine
    Duration
    Single dose
    Key finding

    L-theanine improved reaction time and working memory on cognitive tests in attention-prone adults, without sedation.

    Read on PubMed
How we read the research

We prioritize randomised controlled trials and meta-analyses over single observational studies. Animal and in-vitro data are listed as "mechanistic", they suggest direction, not human effect size.

What we don't do

We don't cherry-pick favourable studies, omit conflicting evidence, or cite industry-funded trials without flagging the conflict of interest where known.

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The research is one thing, what to take, at what dose, paired with what, is another. We compose stacks that turn the evidence into a daily routine.

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Studies referenced are real published research. Summaries are paraphrased for accessibility, for exact methods and full text, click through to PubMed. Educational use only, not medical advice. Consult a qualified clinician before starting any new supplement.