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Nicotinamide Riboside (NIAGEN)

NAD+ precursor (most-studied form)

STRONG EVIDENCEVEGANREAD THE RESEARCH
Written to our editorial standards · reviewed against published research· Updated 2 Jun 2026
Last reviewed: May 30, 2026
QUICK ANSWER

Nicotinamide Riboside: NAD+ precursor (most-studied form). The most clinically-studied NAD+ precursor. Patented NIAGEN form has 20+ published human trials. Standard dose 300 mg, taken in the morning, about $45/month. Evidence rating: strong evidence.

What is Nicotinamide Riboside?

Nicotinamide riboside (NR) is a form of vitamin B3 and a precursor to NAD+. The NIAGEN form, made by ChromaDex, is the most clinically-studied NAD+ booster on the market with over 20 published human trials demonstrating safe and significant elevation of blood NAD+ levels at doses of 100-1000 mg/day. NR has shown benefits for cellular energy, exercise tolerance in older adults, and metabolic markers. Unlike NMN, NIAGEN is GRAS-affirmed by the FDA and NDI-approved as a dietary supplement. Standard daily dose is 300 mg in the morning.

WHY IT MATTERS

The most clinically-studied NAD+ precursor. Patented NIAGEN form has 20+ published human trials.

Where to buy

Tru Niagen Nicotinamide Riboside 300mg
RECOMMENDED
Tru Niagen, Nicotinamide Riboside
300 mg · Morning · ~$45/month

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Common questions

What is Nicotinamide Riboside?
Nicotinamide riboside (NR) is a form of vitamin B3 and a precursor to NAD+. The NIAGEN form, made by ChromaDex, is the most clinically-studied NAD+ booster on the market with over 20 published human trials demonstrating safe and significant elevation of blood NAD+ levels at doses of 100-1000 mg/day. NR has shown benefits for cellular energy, exercise tolerance in older adults, and metabolic markers. Unlike NMN, NIAGEN is GRAS-affirmed by the FDA and NDI-approved as a dietary supplement. Standard daily dose is 300 mg in the morning.
What is Nicotinamide Riboside used for?
NAD+ precursor (most-studied form). The most clinically-studied NAD+ precursor. Patented NIAGEN form has 20+ published human trials.
What is the standard dose of Nicotinamide Riboside?
300 mg, typically taken in the morning. Approximate cost is $45 per month.
How strong is the evidence for Nicotinamide Riboside?
Strong evidence for its primary uses. See the full study list on the research page.

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