Ingredients · Citicoline · Research
Clinical research

What does the research say about Citicoline?

strong evidence

Citicoline (CDP-Choline), Cognizin is the patented form, supports both choline-based acetylcholine synthesis and phosphatidylcholine membrane integrity. Evidence-leading for attention.

Best-evidenced use cases
  • Adolescent attention and processing speed
  • Adult attention performance
  • Stroke recovery (clinical)
  • Age-related memory complaints

2 key studies

Search PubMed for more
  • 01RCT2012Food and Nutrition Sciences

    Citicoline and attention in healthy adolescents

    McGlade et al.
    Sample
    75 healthy adolescent males
    Dose
    250-500 mg/day Cognizin
    Duration
    28 days
    Key finding

    Citicoline significantly improved attention performance and reduced impulsivity vs placebo on continuous performance tasks.

    Read on PubMed
  • 02RCT1996Archives of Neurology

    Citicoline in older adults with age-related memory complaints

    Spiers et al.
    Sample
    95 older adults
    Dose
    1,000 mg/day
    Duration
    3 months
    Key finding

    Citicoline improved word-list recall and other verbal memory measures in adults with age-associated memory impairment.

    Read on PubMed
How we read the research

We prioritize randomised controlled trials and meta-analyses over single observational studies. Animal and in-vitro data are listed as "mechanistic", they suggest direction, not human effect size.

What we don't do

We don't cherry-pick favourable studies, omit conflicting evidence, or cite industry-funded trials without flagging the conflict of interest where known.

Make it actionable

See Citicoline in a personalised stack

The research is one thing, what to take, at what dose, paired with what, is another. We compose stacks that turn the evidence into a daily routine.

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Studies referenced are real published research. Summaries are paraphrased for accessibility, for exact methods and full text, click through to PubMed. Educational use only, not medical advice. Consult a qualified clinician before starting any new supplement.