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Citicoline (CDP-Choline)

Focus · attention · brain energy

Strong evidenceVegan155 studies on PubMedRead the research
Written to our editorial standards · reviewed against published research· Updated 30 May 2026
Last reviewed: May 30, 2026

Citicoline: Focus · attention · brain energy. Choline source that converts into both phosphatidylcholine (membranes) and acetylcholine (signaling). Sharper than plain choline. Standard dose 250 mg, taken in the morning, about $26/month. Evidence rating: strong evidence.

Where to buy

Jarrow Formulas Citicoline (CDP-Choline) 250mg
Recommended
Cognizin, Citicoline
250 mg · Morning · ~$26/month

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All product options

Jarrow Formulas Citicoline (CDP-Choline) 250mgBestseller
Citicoline (CDP-Choline) 250mg
Jarrow Formulas
120 capsules · $28 · ★ 4.7
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Jarrow Formulas Citicoline (CDP Choline)Bestseller
Citicoline (CDP Choline)
Jarrow Formulas
60 capsules · $25 · ★ 4.7
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NOW Foods CDP-CholineBest Value
CDP-Choline
NOW Foods
50 veg caps · $20 · ★ 4.6
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Nutricost Citicoline (CDP Choline)Premium
Citicoline (CDP Choline)
Nutricost
60 capsules · $22 · ★ 4.6
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Double Wood CiticolinePremium
Citicoline
Double Wood
60 capsules · $20 · ★ 4.5
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What is Citicoline?

Citicoline, also known as CDP-choline, is a naturally occurring compound that provides both choline (a precursor to the neurotransmitter acetylcholine) and cytidine (a precursor to uridine, important for synaptic plasticity). The Cognizin branded form has been used in placebo-controlled trials showing improvements in attention, focus, and information processing speed in healthy adults. Citicoline also supports phosphatidylcholine synthesis in neuronal membranes, contributing to long-term brain structural integrity. Standard daily doses range from 250-500 mg in the morning. It is one of the few nootropics with both acute and cumulative effects.

Choline source that converts into both phosphatidylcholine (membranes) and acetylcholine (signaling). Sharper than plain choline.

Stacks that include Citicoline

✦
The Focus Stack
Sharper mind, calmer attention.

Best for your goal

Interactions

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Common questions

What is Citicoline?
Citicoline, also known as CDP-choline, is a naturally occurring compound that provides both choline (a precursor to the neurotransmitter acetylcholine) and cytidine (a precursor to uridine, important for synaptic plasticity). The Cognizin branded form has been used in placebo-controlled trials showing improvements in attention, focus, and information processing speed in healthy adults. Citicoline also supports phosphatidylcholine synthesis in neuronal membranes, contributing to long-term brain structural integrity. Standard daily doses range from 250-500 mg in the morning. It is one of the few nootropics with both acute and cumulative effects.
What is Citicoline used for?
Focus · attention · brain energy. Choline source that converts into both phosphatidylcholine (membranes) and acetylcholine (signaling). Sharper than plain choline.
What is the standard dose of Citicoline?
250 mg, typically taken in the morning. Approximate cost is $26 per month.
How strong is the evidence for Citicoline?
Strong evidence for its primary uses. See the full study list on the research page.

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