D-Mannose
Urinary tract comfort
D-Mannose: Urinary tract comfort. A simple sugar that helps flush bacteria from the urinary tract, popular for urinary comfort and prevention. Standard dose 2,000 mg, taken in the morning, about $14/month. Evidence rating: moderate evidence.
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What is D-Mannose?
D-mannose is a naturally occurring simple sugar, related to glucose, that is poorly metabolized and passes largely unchanged into the urine. There it can bind to the type of bacteria most often behind urinary discomfort, helping wash them out before they stick to the bladder wall. Several trials, mostly in women prone to recurring urinary issues, suggest D-mannose can reduce how often these episodes return, with tolerability similar to placebo. It is generally well tolerated, with loose stools the main complaint at high doses. A common approach is around 2 g daily for maintenance, taken with plenty of water. It supports comfort and prevention and is not a substitute for treating an active infection.
A simple sugar that helps flush bacteria from the urinary tract, popular for urinary comfort and prevention.
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