Best supplements for gut health.

Probiotics, prebiotics, and gut-lining support with evidence for digestion, bloating, and a healthier microbiome.

Written to our editorial standards · reviewed against published research· Updated 2 Jun 2026
Each pick is evidence-graded · we don't sell supplements
  1. 1Saccharomyces boulardiiVery strongA beneficial yeast probiotic. The best-evidenced supplement for preventing antibiotic-associated diarrhea.5 billion CFU · morning · ~$22/mo
  2. 2Magnesium CitrateStrongHigher-absorption, mildly laxative form of magnesium. A solid daily option when bowel regularity is also a goal.400 mg elemental · evening · ~$11/mo
  3. 3Berberine HClStrongBotanical compound that activates AMPK, supports healthy blood glucose, lipid profile, and metabolic flexibility.500 mg · midday · ~$22/mo
  4. 4Multi-Strain ProbioticModerateSupports digestive balance, immune signalling, and the gut-brain axis that influences mood and cognition.50B CFU, 15 strains · morning · ~$35/mo
  5. 5Psyllium Husk PowderVery strongSoluble fiber with strong evidence for cholesterol reduction, blood sugar moderation, and bowel regularity.5 g (1 tbsp) · morning · ~$10/mo
  6. 6Ginger Root ExtractStrongThree thousand years of digestive use, now backed by clinical evidence for nausea, IBS symptoms, and inflammation modulation.500 mg standardised · morning · ~$11/mo
  7. 7Zinc-CarnosineStrongA chelated form of zinc and L-carnosine that adheres to the stomach lining. Heals erosions and supports H. pylori protocols.75 mg · morning · ~$26/mo
  8. 8LactoferrinStrongA milk protein with broad-spectrum antimicrobial action and a powerful immune modulator. Also boosts iron absorption.250 mg · morning · ~$32/mo
  9. 9L-Glutamine PowderModerateThe primary fuel for intestinal cells and immune cells. Useful during high stress, intense training, or gut barrier issues.5 g · morning · ~$18/mo
  10. 10Digestive EnzymesModerateBroad-spectrum plant enzymes that help break down proteins, fats, and carbs, useful for bloating or low stomach acid.1 capsule with meals · midday · ~$24/mo
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Common questions

What are the best supplements for gut health?
A quality probiotic plus a prebiotic fibre (a 'synbiotic') supports the microbiome; L-glutamine and zinc-carnosine support the gut lining; digestive enzymes help with breakdown.
Do probiotics help with bloating?
For some people, yes, particularly specific strains. Pairing a probiotic with a prebiotic and easing into fibre (to avoid initial gas) tends to work best.

Educational use only, not medical advice. Always consult a qualified clinician before starting supplements, especially if you take medication or are pregnant or nursing.