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AMINO ACIDS

L-Glutamine Powder

Gut lining · immune · recovery

MODERATE EVIDENCEVEGANREAD THE RESEARCH
Written to our editorial standards · reviewed against published research· Updated 2 Jun 2026
Last reviewed: May 30, 2026
QUICK ANSWER

L-Glutamine Powder: Gut lining · immune · recovery. The primary fuel for intestinal cells and immune cells. Useful during high stress, intense training, or gut barrier issues. Standard dose 5 g, taken in the morning, about $18/month. Evidence rating: moderate evidence.

What is L-Glutamine Powder?

L-Glutamine is the most abundant amino acid in the bloodstream and the primary fuel source for two of the body's most rapidly dividing cell populations: enterocytes (the cells lining the small intestine) and immune cells. Under normal conditions, the body produces enough glutamine to meet demand. But during prolonged stress, intense endurance training, injury recovery, or compromised gut barrier function, glutamine becomes 'conditionally essential.' Supplementation may support gut barrier integrity, immune resilience after hard training, and recovery from physical stressors. Standard doses are 5-10 g per day, mixed in water or a non-acidic beverage on an empty stomach.

WHY IT MATTERS

The primary fuel for intestinal cells and immune cells. Useful during high stress, intense training, or gut barrier issues.

Natural food sources

Where possible, get L-Glutamine Powder from whole foods first. Common dietary sources include:

BeefEggsDairyTofuCabbage

Where to buy

Thorne L-Glutamine Powder
RECOMMENDED
Thorne, L-Glutamine Powder
5 g · Morning · ~$18/month

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Stacks that include L-Glutamine Powder

❀
The Gut Reset Stack
Repair the lining. Rebalance the microbiome.

Best for your goal

Interactions

Other amino acids

L-Theanine (Suntheanine)
Calm focus · stress
Glycine
Sleep depth · core body temperature
N-Acetyl Cysteine (NAC)
Liver · antioxidant · respiratory
Taurine
Heart · sleep · cellular hydration

Common questions

What is L-Glutamine Powder?
L-Glutamine is the most abundant amino acid in the bloodstream and the primary fuel source for two of the body's most rapidly dividing cell populations: enterocytes (the cells lining the small intestine) and immune cells. Under normal conditions, the body produces enough glutamine to meet demand. But during prolonged stress, intense endurance training, injury recovery, or compromised gut barrier function, glutamine becomes 'conditionally essential.' Supplementation may support gut barrier integrity, immune resilience after hard training, and recovery from physical stressors. Standard doses are 5-10 g per day, mixed in water or a non-acidic beverage on an empty stomach.
What is L-Glutamine Powder used for?
Gut lining · immune · recovery. The primary fuel for intestinal cells and immune cells. Useful during high stress, intense training, or gut barrier issues.
What is the standard dose of L-Glutamine Powder?
5 g, typically taken in the morning. Approximate cost is $18 per month.
How strong is the evidence for L-Glutamine Powder?
Moderate evidence for its primary uses. See the full study list on the research page.

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