Devil's Claw
Joint · lower-back comfort
Devil's Claw: Joint · lower-back comfort. A South African root used traditionally to ease joint and lower-back discomfort, standardized to harpagoside. Standard dose 600 mg (harpagoside), taken in the morning, about $13/month. Evidence rating: moderate evidence.
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What is Devil's Claw?
Devil's claw (Harpagophytum procumbens) is a plant native to southern Africa, named for its hooked fruit, whose root has been used traditionally for joint and musculoskeletal discomfort. Its iridoid compounds, chiefly harpagoside, show anti-inflammatory activity, and several clinical trials report that standardized extracts ease osteoarthritis and lower-back discomfort, sometimes comparably to common options, over a few weeks. It is generally well tolerated, with mild digestive upset the usual complaint. Because it may increase stomach acid and has mild effects on blood and heart rhythm, it should be avoided by people prone to ulcers and used cautiously with blood thinners or heart medication. Extracts standardized to harpagoside, around 600 mg daily, are typical.
A South African root used traditionally to ease joint and lower-back discomfort, standardized to harpagoside.
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