Ingredients · Vitamin C · Research
Clinical research

What does the research say about Vitamin C?

strong evidence

Vitamin C (ascorbic acid) is essential for collagen synthesis, neurotransmitter formation, and antioxidant defense. The well-evidenced uses are around cold duration and exercise stress.

Best-evidenced use cases
  • Cold duration reduction (especially in active people)
  • Iron absorption enhancement
  • Daily antioxidant support
  • Wound healing
  • Collagen synthesis pairing

3 key studies

Search PubMed for more
  • 01Meta-analysis2013Cochrane Database of Systematic Reviews

    Vitamin C for preventing and treating the common cold

    Hemilä & Chalker
    Sample
    29 RCTs · 11,306 participants
    Dose
    ≥200 mg/day
    Duration
    Ongoing
    Key finding

    Regular vitamin C didn't reduce cold incidence in the general population, but reduced cold duration by 8% in adults and 14% in children. Larger benefit in athletes (52% reduction in incidence).

    Read on PubMed
  • 02Systematic Review2015Sports Medicine

    Vitamin C and exercise-induced oxidative stress

    Braakhuis & Hopkins
    Sample
    Multiple RCTs reviewed
    Dose
    200-1,000 mg/day
    Duration
    Variable
    Key finding

    Moderate vitamin C (200-500 mg) supports recovery in athletes. Mega-doses (>1 g) may blunt training adaptations, moderation matters.

    Read on PubMed
  • 03RCT2001American Journal of Clinical Nutrition

    Vitamin C and iron absorption

    Cook & Reddy
    Sample
    Crossover study, healthy adults
    Dose
    100 mg vitamin C with iron
    Duration
    Per meal
    Key finding

    Vitamin C taken with iron-rich meals dramatically enhances non-heme iron absorption, clinically meaningful for vegetarians and women with low ferritin.

    Read on PubMed
How we read the research

We prioritize randomised controlled trials and meta-analyses over single observational studies. Animal and in-vitro data are listed as "mechanistic", they suggest direction, not human effect size.

What we don't do

We don't cherry-pick favourable studies, omit conflicting evidence, or cite industry-funded trials without flagging the conflict of interest where known.

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Studies referenced are real published research. Summaries are paraphrased for accessibility, for exact methods and full text, click through to PubMed. Educational use only, not medical advice. Consult a qualified clinician before starting any new supplement.