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VITAMINS

Vitamin C (Buffered)

Immune · antioxidant · collagen synthesis

STRONG EVIDENCEVEGANREAD THE RESEARCH
Written to our editorial standards · reviewed against published research· Updated 2 Jun 2026
Last reviewed: May 30, 2026
QUICK ANSWER

Vitamin C: Immune · antioxidant · collagen synthesis. Immune support, antioxidant defense, and collagen synthesis. Buffered form is gentler on the stomach. Standard dose 1000 mg, taken in the morning, about $9/month. Evidence rating: strong evidence.

What is Vitamin C?

Vitamin C is a water-soluble vitamin that the human body, unlike most mammals, cannot synthesize. It functions as a powerful antioxidant, a cofactor for collagen synthesis (essential for skin, blood vessels, and connective tissue), and a key player in immune defense. Buffered vitamin C is paired with minerals like calcium, magnesium, or potassium, raising the pH and making it gentler on the stomach than ascorbic acid alone, particularly important at higher doses. While the 90 mg daily reference intake prevents scurvy, optimal intake for general health is debated but often cited as 500-1,000 mg per day. Doses above 2 g can cause loose stools.

WHY IT MATTERS

Immune support, antioxidant defense, and collagen synthesis. Buffered form is gentler on the stomach.

Natural food sources

Where possible, get Vitamin C from whole foods first. Common dietary sources include:

Citrus fruits (oranges)Bell peppersStrawberriesBroccoliKiwi

Where to buy

NOW Foods Vitamin C-1000 with Rose Hips
RECOMMENDED
Nature's Way, Vitamin C
1000 mg · Morning · ~$9/month

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All product options

NOW Foods Vitamin C-1000 with Rose HipsBESTSELLER
Vitamin C-1000 with Rose Hips
NOW Foods
250 tablets · $14 · ★ 4.8
Buy on iHerb →Buy on Amazon →
Nature's Way Vitamin C BufferedBEST VALUE
Vitamin C Buffered
Nature's Way
100 capsules · $11 · ★ 4.7
Buy on iHerb →Buy on Amazon →
Thorne Vitamin C with FlavonoidsPREMIUM
Vitamin C with Flavonoids
Thorne
90 capsules · $23 · ★ 4.8
Buy on iHerb →Buy on Amazon →

Stacks that include Vitamin C

The Immunity Stack
Resilient through every season.
The Beauty Stack
Inside-out support for skin, hair, and nails.

Best for your goal

Interactions

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Common questions

What is Vitamin C?
Vitamin C is a water-soluble vitamin that the human body, unlike most mammals, cannot synthesize. It functions as a powerful antioxidant, a cofactor for collagen synthesis (essential for skin, blood vessels, and connective tissue), and a key player in immune defense. Buffered vitamin C is paired with minerals like calcium, magnesium, or potassium, raising the pH and making it gentler on the stomach than ascorbic acid alone, particularly important at higher doses. While the 90 mg daily reference intake prevents scurvy, optimal intake for general health is debated but often cited as 500-1,000 mg per day. Doses above 2 g can cause loose stools.
What is Vitamin C used for?
Immune · antioxidant · collagen synthesis. Immune support, antioxidant defense, and collagen synthesis. Buffered form is gentler on the stomach.
What is the standard dose of Vitamin C?
1000 mg, typically taken in the morning. Approximate cost is $9 per month.
How strong is the evidence for Vitamin C?
Strong evidence for its primary uses. See the full study list on the research page.

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