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VITAMINS

Vitamin D3 + K2

Energy · bone · immune

STRONG EVIDENCECORE INGREDIENTREAD THE RESEARCH
Written to our editorial standards · reviewed against published research· Updated 2 Jun 2026
Last reviewed: May 30, 2026
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Vitamin D3 + K2: Energy · bone · immune. Supports mood, immune function, bone health, and calcium routing. Especially valuable indoors or above 40° latitude. Standard dose 5000 IU D3 + 90 mcg K2, taken in the morning, about $12/month. Evidence rating: strong evidence.

What is Vitamin D3 + K2?

Vitamin D3 (cholecalciferol) is the form your skin produces from sunlight and the form your body uses for hundreds of processes, from immune function and mood regulation to bone density and calcium absorption. Modern life keeps most adults indoors, and roughly 40% of the global population is now estimated to have insufficient D3 levels. Pairing D3 with vitamin K2 (MK-7) is essential: K2 directs calcium into bones and away from arteries, mitigating the cardiovascular risk that high-dose D3 alone can carry. The combined daily dose of 5,000 IU D3 with 90 mcg K2 is well-evidenced for adults at all latitudes.

WHY IT MATTERS

Supports mood, immune function, bone health, and calcium routing. Especially valuable indoors or above 40° latitude.

Natural food sources

Where possible, get Vitamin D3 + K2 from whole foods first. Common dietary sources include:

Fatty fish (salmon, mackerel)Egg yolksFortified milk & cerealsSunlight (D3 synthesis)Natto & hard cheeses (K2)

Where to buy

NOW Foods Vitamin D-3 & K-2
RECOMMENDED
Sports Research, Vitamin D3 + K2
5000 IU D3 + 90 mcg K2 · Morning · ~$12/month

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All product options

NOW Foods Vitamin D-3 & K-2BESTSELLER
Vitamin D-3 & K-2
NOW Foods
120 veg capsules · $12 · ★ 4.8
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Sports Research Vitamin D3 + K2EDITOR'S PICK
Vitamin D3 + K2
Sports Research
60 softgels · $15 · ★ 4.8
Buy on iHerb →Buy on Amazon →
Doctor's Best Vitamin D3 5000 IU + K2BEST VALUE
Vitamin D3 5000 IU + K2
Doctor's Best
60 softgels · $11 · ★ 4.7
Buy on iHerb →Buy on Amazon →

Stacks that include Vitamin D3 + K2

The Foundation Stack
The three supplements almost everyone benefits from.
The Energy Stack
Steady output, no caffeine crashes.
The Immunity Stack
Resilient through every season.
The Vegan Essentials
Plant-based, perfectly covered.
The Healthy Aging Stack
Age slower. Move better. Stay sharp.
The Hormonal Balance Stack
Smoother cycles, steadier mood.
The Menopause Support Stack
Steadier hormones through the transition.

Best for your goal

Interactions

Related biomarkers

Other vitamins

Whole-food Multivitamin
Baseline nutrition
Methyl-B12
Energy · nerves · cognition
B-Complex
Energy · stress · methylation
Vitamin C (Buffered)
Immune · antioxidant · collagen synthesis

Common questions

What is Vitamin D3 + K2?
Vitamin D3 (cholecalciferol) is the form your skin produces from sunlight and the form your body uses for hundreds of processes, from immune function and mood regulation to bone density and calcium absorption. Modern life keeps most adults indoors, and roughly 40% of the global population is now estimated to have insufficient D3 levels. Pairing D3 with vitamin K2 (MK-7) is essential: K2 directs calcium into bones and away from arteries, mitigating the cardiovascular risk that high-dose D3 alone can carry. The combined daily dose of 5,000 IU D3 with 90 mcg K2 is well-evidenced for adults at all latitudes.
What is Vitamin D3 + K2 used for?
Energy · bone · immune. Supports mood, immune function, bone health, and calcium routing. Especially valuable indoors or above 40° latitude.
What is the standard dose of Vitamin D3 + K2?
5000 IU D3 + 90 mcg K2, typically taken in the morning. Approximate cost is $12 per month.
How strong is the evidence for Vitamin D3 + K2?
Strong evidence for its primary uses. See the full study list on the research page.

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