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Citicoline, also known as CDP-choline, is a naturally occurring compound that provides both choline (a precursor to the neurotransmitter acetylcholine) and cytidine (a precursor to uridine, important for synaptic plasticity). The Cognizin branded form has been used in placebo-controlled trials showing improvements in attention, focus, and information processing speed in healthy adults. Citicoline also supports phosphatidylcholine synthesis in neuronal membranes, contributing to long-term brain structural integrity. Standard daily doses range from 250-500 mg in the morning. It is one of the few nootropics with both acute and cumulative effects.
Choline source that converts into both phosphatidylcholine (membranes) and acetylcholine (signaling). Sharper than plain choline.
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