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VITAMINS

Choline Bitartrate

Liver · brain · acetylcholine

STRONG EVIDENCEVEGANREAD THE RESEARCH
Written to our editorial standards · reviewed against published research· Updated 2 Jun 2026
Last reviewed: May 30, 2026
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Choline Bitartrate: Liver · brain · acetylcholine. Essential nutrient most adults don't get enough of. Powers liver fat metabolism and acetylcholine production for memory and focus. Standard dose 500 mg, taken in the morning, about $11/month. Evidence rating: strong evidence.

What is Choline Bitartrate?

Choline is an essential nutrient that the body cannot produce in adequate amounts. Despite its critical roles in liver fat metabolism, neurotransmitter synthesis, and cell membrane structure, an estimated 90% of adults fall short of the recommended daily intake. Choline is the precursor to acetylcholine, the neurotransmitter that governs memory, focus, and the brain-muscle connection, and to phosphatidylcholine, a structural backbone of every cell membrane. Adequate choline supports liver health (preventing fat accumulation), cognitive function, and is especially important during pregnancy for fetal brain development. Standard doses are 250-1,000 mg per day with food.

WHY IT MATTERS

Essential nutrient most adults don't get enough of. Powers liver fat metabolism and acetylcholine production for memory and focus.

Natural food sources

Where possible, get Choline Bitartrate from whole foods first. Common dietary sources include:

Egg yolksBeef liverChickenSoybeansCruciferous vegetables

Where to buy

NOW Foods Choline & Inositol 500mg
RECOMMENDED
NOW Foods, Choline Bitartrate
500 mg · Morning · ~$11/month

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Common questions

What is Choline Bitartrate?
Choline is an essential nutrient that the body cannot produce in adequate amounts. Despite its critical roles in liver fat metabolism, neurotransmitter synthesis, and cell membrane structure, an estimated 90% of adults fall short of the recommended daily intake. Choline is the precursor to acetylcholine, the neurotransmitter that governs memory, focus, and the brain-muscle connection, and to phosphatidylcholine, a structural backbone of every cell membrane. Adequate choline supports liver health (preventing fat accumulation), cognitive function, and is especially important during pregnancy for fetal brain development. Standard doses are 250-1,000 mg per day with food.
What is Choline Bitartrate used for?
Liver · brain · acetylcholine. Essential nutrient most adults don't get enough of. Powers liver fat metabolism and acetylcholine production for memory and focus.
What is the standard dose of Choline Bitartrate?
500 mg, typically taken in the morning. Approximate cost is $11 per month.
How strong is the evidence for Choline Bitartrate?
Strong evidence for its primary uses. See the full study list on the research page.

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