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Phosphatidylcholine (PC)

Liver · brain · cell membrane integrity

Moderate evidenceVegan615 studies on PubMedRead the research
Written to our editorial standards · reviewed against published research· Updated 30 May 2026
Last reviewed: May 30, 2026

Phosphatidylcholine: Liver · brain · cell membrane integrity. The primary phospholipid in cell membranes. Critical for liver function (fat transport) and brain plasticity. Standard dose 1300 mg, taken in the morning, about $32/month. Evidence rating: moderate evidence.

Where to buy

BodyBio PC (Phosphatidylcholine) Liquid
Recommended
Bodybio, Phosphatidylcholine
1300 mg · Morning · ~$32/month

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BodyBio PC (Phosphatidylcholine) LiquidBestseller
PC (Phosphatidylcholine) Liquid
BodyBio
16 fl oz · $75 · ★ 4.7
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Phosphatidyl Choline
NOW Foods
100 softgels · $20 · ★ 4.6
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Jarrow Formulas PC PhosphatidylcholineBest Value
PC Phosphatidylcholine
Jarrow Formulas
120 softgels · $24 · ★ 4.6
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BodyBio PC PhosphatidylcholinePremium
PC Phosphatidylcholine
BodyBio
100 softgels · $45 · ★ 4.7
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Double Wood PhosphatidylcholinePremium
Phosphatidylcholine
Double Wood
210 capsules · $22 · ★ 4.5
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What is Phosphatidylcholine?

Phosphatidylcholine (PC) is the most abundant phospholipid in every cell membrane in the human body, where it provides structural integrity and fluidity to the lipid bilayer. The liver depends on PC to package and transport fats out to circulation; deficiency contributes to fatty liver accumulation. In the brain, PC is the precursor to acetylcholine and a structural backbone of myelin and synaptic membranes. Supplementation supports liver health, cell membrane repair, and cognitive function with age. Highly purified PC formulations (such as BodyBio PC) deliver intact phospholipids in a lipid carrier. Standard doses are 900-2,600 mg per day.

The primary phospholipid in cell membranes. Critical for liver function (fat transport) and brain plasticity.

Natural food sources

Where possible, get Phosphatidylcholine from whole foods first. Common dietary sources include:

Egg yolksSoybeansLiverSunflower seeds

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Common questions

What is Phosphatidylcholine?
Phosphatidylcholine (PC) is the most abundant phospholipid in every cell membrane in the human body, where it provides structural integrity and fluidity to the lipid bilayer. The liver depends on PC to package and transport fats out to circulation; deficiency contributes to fatty liver accumulation. In the brain, PC is the precursor to acetylcholine and a structural backbone of myelin and synaptic membranes. Supplementation supports liver health, cell membrane repair, and cognitive function with age. Highly purified PC formulations (such as BodyBio PC) deliver intact phospholipids in a lipid carrier. Standard doses are 900-2,600 mg per day.
What is Phosphatidylcholine used for?
Liver · brain · cell membrane integrity. The primary phospholipid in cell membranes. Critical for liver function (fat transport) and brain plasticity.
What is the standard dose of Phosphatidylcholine?
1300 mg, typically taken in the morning. Approximate cost is $32 per month.
How strong is the evidence for Phosphatidylcholine?
Moderate evidence for its primary uses. See the full study list on the research page.

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