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Phosphatidylcholine (PC)

Liver · brain · cell membrane integrity

MODERATE EVIDENCEVEGANREAD THE RESEARCH
Written to our editorial standards · reviewed against published research· Updated 2 Jun 2026
Last reviewed: May 30, 2026
QUICK ANSWER

Phosphatidylcholine: Liver · brain · cell membrane integrity. The primary phospholipid in cell membranes. Critical for liver function (fat transport) and brain plasticity. Standard dose 1300 mg, taken in the morning, about $32/month. Evidence rating: moderate evidence.

What is Phosphatidylcholine?

Phosphatidylcholine (PC) is the most abundant phospholipid in every cell membrane in the human body, where it provides structural integrity and fluidity to the lipid bilayer. The liver depends on PC to package and transport fats out to circulation; deficiency contributes to fatty liver accumulation. In the brain, PC is the precursor to acetylcholine and a structural backbone of myelin and synaptic membranes. Supplementation supports liver health, cell membrane repair, and cognitive function with age. Highly purified PC formulations (such as BodyBio PC) deliver intact phospholipids in a lipid carrier. Standard doses are 900-2,600 mg per day.

WHY IT MATTERS

The primary phospholipid in cell membranes. Critical for liver function (fat transport) and brain plasticity.

Natural food sources

Where possible, get Phosphatidylcholine from whole foods first. Common dietary sources include:

Egg yolksSoybeansLiverSunflower seeds

Where to buy

BodyBio PC (Phosphatidylcholine) Liquid
RECOMMENDED
Bodybio, Phosphatidylcholine
1300 mg · Morning · ~$32/month

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Common questions

What is Phosphatidylcholine?
Phosphatidylcholine (PC) is the most abundant phospholipid in every cell membrane in the human body, where it provides structural integrity and fluidity to the lipid bilayer. The liver depends on PC to package and transport fats out to circulation; deficiency contributes to fatty liver accumulation. In the brain, PC is the precursor to acetylcholine and a structural backbone of myelin and synaptic membranes. Supplementation supports liver health, cell membrane repair, and cognitive function with age. Highly purified PC formulations (such as BodyBio PC) deliver intact phospholipids in a lipid carrier. Standard doses are 900-2,600 mg per day.
What is Phosphatidylcholine used for?
Liver · brain · cell membrane integrity. The primary phospholipid in cell membranes. Critical for liver function (fat transport) and brain plasticity.
What is the standard dose of Phosphatidylcholine?
1300 mg, typically taken in the morning. Approximate cost is $32 per month.
How strong is the evidence for Phosphatidylcholine?
Moderate evidence for its primary uses. See the full study list on the research page.

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