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Urolithin A (Mitopure)

Mitophagy · muscle function · cellular renewal

STRONG EVIDENCEVEGANREAD THE RESEARCH
Written to our editorial standards · reviewed against published research· Updated 2 Jun 2026
Last reviewed: May 30, 2026
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Urolithin A: Mitophagy · muscle function · cellular renewal. Triggers mitophagy, the cellular recycling of damaged mitochondria. Only ~40% of adults make enough naturally. Standard dose 500 mg, taken in the morning, about $65/month. Evidence rating: strong evidence.

What is Urolithin A?

Urolithin A is a postbiotic compound produced when gut bacteria metabolize ellagitannins from pomegranates and certain berries, but only about 40% of adults harbor the right microbiome to produce it in meaningful amounts. The patented Mitopure form, developed by Swiss biotech Amazentis and clinically validated in trials, delivers a standardized 500 mg dose. Human trials show urolithin A induces mitophagy (the body's quality-control process for damaged mitochondria), improves muscle endurance, and reduces inflammatory markers in adults 40+. It's considered one of the most promising longevity ingredients of the decade.

WHY IT MATTERS

Triggers mitophagy, the cellular recycling of damaged mitochondria. Only ~40% of adults make enough naturally.

Where to buy

Timeline Mitopure Urolithin A
RECOMMENDED
Timeline, Urolithin A
500 mg · Morning · ~$65/month

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Common questions

What is Urolithin A?
Urolithin A is a postbiotic compound produced when gut bacteria metabolize ellagitannins from pomegranates and certain berries, but only about 40% of adults harbor the right microbiome to produce it in meaningful amounts. The patented Mitopure form, developed by Swiss biotech Amazentis and clinically validated in trials, delivers a standardized 500 mg dose. Human trials show urolithin A induces mitophagy (the body's quality-control process for damaged mitochondria), improves muscle endurance, and reduces inflammatory markers in adults 40+. It's considered one of the most promising longevity ingredients of the decade.
What is Urolithin A used for?
Mitophagy · muscle function · cellular renewal. Triggers mitophagy, the cellular recycling of damaged mitochondria. Only ~40% of adults make enough naturally.
What is the standard dose of Urolithin A?
500 mg, typically taken in the morning. Approximate cost is $65 per month.
How strong is the evidence for Urolithin A?
Strong evidence for its primary uses. See the full study list on the research page.

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