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HEART & CIRCULATION

Citrus Bergamot (BPF)

Cholesterol · cardiometabolic · liver

STRONG EVIDENCEVEGANREAD THE RESEARCH
Written to our editorial standards · reviewed against published research· Updated 2 Jun 2026
Last reviewed: May 30, 2026
QUICK ANSWER

Citrus Bergamot: Cholesterol · cardiometabolic · liver. A polyphenol extract that significantly lowers LDL cholesterol and triglycerides in clinical trials. Statin-comparable in some studies. Standard dose 500 mg, taken in the evening, about $28/month. Evidence rating: strong evidence.

What is Citrus Bergamot?

Citrus bergamot (Citrus bergamia) is a citrus fruit grown almost exclusively in the Calabria region of southern Italy. Its polyphenol fraction (Bergamot Polyphenolic Fraction, BPF), standardized to brutieridin, melitidin, and other flavonoids, has demonstrated meaningful lipid-lowering effects in randomized trials: typical reductions of 24-36% in LDL-cholesterol and 30% in triglycerides over 6 months. Unlike statins, bergamot does not deplete CoQ10 and may improve insulin sensitivity. Standard dose is 500-1500 mg of standardized extract per day, with the evening meal.

WHY IT MATTERS

A polyphenol extract that significantly lowers LDL cholesterol and triglycerides in clinical trials. Statin-comparable in some studies.

Natural food sources

Where possible, get Citrus Bergamot from whole foods first. Common dietary sources include:

Bergamot orangesBergamot juiceEarl Grey tea

Where to buy

Jarrow Formulas Citrus Bergamot (BPF) 500mg
RECOMMENDED
Jarrow Formulas, Citrus Bergamot
500 mg · Evening · ~$28/month

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Interactions

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Common questions

What is Citrus Bergamot?
Citrus bergamot (Citrus bergamia) is a citrus fruit grown almost exclusively in the Calabria region of southern Italy. Its polyphenol fraction (Bergamot Polyphenolic Fraction, BPF), standardized to brutieridin, melitidin, and other flavonoids, has demonstrated meaningful lipid-lowering effects in randomized trials: typical reductions of 24-36% in LDL-cholesterol and 30% in triglycerides over 6 months. Unlike statins, bergamot does not deplete CoQ10 and may improve insulin sensitivity. Standard dose is 500-1500 mg of standardized extract per day, with the evening meal.
What is Citrus Bergamot used for?
Cholesterol · cardiometabolic · liver. A polyphenol extract that significantly lowers LDL cholesterol and triglycerides in clinical trials. Statin-comparable in some studies.
What is the standard dose of Citrus Bergamot?
500 mg, typically taken in the evening. Approximate cost is $28 per month.
How strong is the evidence for Citrus Bergamot?
Strong evidence for its primary uses. See the full study list on the research page.

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