Best supplements for heart health.

Supplements with cardiovascular evidence, for cholesterol, triglycerides, blood pressure, and heart-muscle energy.

Written to our editorial standards · reviewed against published research· Updated 2 Jun 2026
Each pick is evidence-graded · we don't sell supplements
  1. 1Omega-3 Fish OilVery strongHigh-EPA fish oil supports cardiovascular health, brain function, mood, and the inflammation curve after training.1250 mg EPA+DHA · morning · ~$22/mo
  2. 2Algae Omega-3 EPA/DHAStrongPlant-based EPA/DHA from algae, the same omega-3s as fish oil, since fish get them from algae in the first place.500 mg EPA+DHA · morning · ~$28/mo
  3. 3Vitamin K2 MK-7StrongRoutes calcium into bones and away from arteries. Critical companion when supplementing high-dose vitamin D3.100 mcg · morning · ~$16/mo
  4. 4Berberine HClStrongBotanical compound that activates AMPK, supports healthy blood glucose, lipid profile, and metabolic flexibility.500 mg · midday · ~$22/mo
  5. 5Psyllium Husk PowderVery strongSoluble fiber with strong evidence for cholesterol reduction, blood sugar moderation, and bowel regularity.5 g (1 tbsp) · morning · ~$10/mo
  6. 6TaurineStrongConditionally-essential amino acid that supports cardiovascular function, electrical signaling in muscles, and neurological calm.2000 mg · evening · ~$12/mo
  7. 7TMGStrongA methyl donor that lowers homocysteine and replenishes methyl groups consumed by NAD+ precursors like NMN and NR.1000 mg · morning · ~$14/mo
  8. 8Green Tea EGCGStrongConcentrated EGCG, the most-studied catechin. Supports thermogenesis, cardiovascular markers, and acts as a potent antioxidant.400 mg EGCG · morning · ~$18/mo
  9. 9Aged Garlic ExtractStrongAged at low heat for 20+ months, odorless, with concentrated, stable bioactives clinically shown to support healthy cholesterol and BP.1200 mg · morning · ~$22/mo
  10. 10CoQ10StrongThe active form of CoQ10, fuels cellular energy production and supports cardiovascular function. More relevant after 40.100 mg ubiquinol · morning · ~$26/mo
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Common questions

What are the best supplements for heart health?
Omega-3 (for triglycerides), CoQ10 (heart-muscle energy, especially on statins), and bergamot or aged garlic for cholesterol support have the most evidence.
Which supplement lowers cholesterol?
Bergamot, red yeast rice, and aged garlic have evidence for lowering cholesterol, and omega-3 lowers triglycerides. Discuss with your doctor, particularly alongside statins.

Educational use only, not medical advice. Always consult a qualified clinician before starting supplements, especially if you take medication or are pregnant or nursing.