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Vitamin K2 MK-7

Bone · arterial calcium routing

STRONG EVIDENCEREAD THE RESEARCH
Written to our editorial standards · reviewed against published research· Updated 2 Jun 2026
Last reviewed: May 30, 2026
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Vitamin K2 MK-7: Bone · arterial calcium routing. Routes calcium into bones and away from arteries. Critical companion when supplementing high-dose vitamin D3. Standard dose 100 mcg, taken in the morning, about $16/month. Evidence rating: strong evidence.

What is Vitamin K2 MK-7?

Vitamin K2 (menaquinone-7, or MK-7) is the long-acting, animal-derived form of vitamin K that activates two proteins central to calcium routing in the body: osteocalcin, which directs calcium into bone, and matrix Gla protein, which keeps calcium out of arteries. While vitamin K1 (from leafy greens) primarily supports blood clotting, K2 is increasingly recognized as essential for bone density and cardiovascular health. The MK-7 form has a half-life of 72 hours, far longer than MK-4, making once-daily dosing effective. It is especially important to pair with vitamin D3 supplementation. Typical doses are 90-200 mcg per day.

WHY IT MATTERS

Routes calcium into bones and away from arteries. Critical companion when supplementing high-dose vitamin D3.

Natural food sources

Where possible, get Vitamin K2 MK-7 from whole foods first. Common dietary sources include:

NattoHard cheesesEgg yolksChicken

Where to buy

Doctor's Best Natural Vitamin K2 MK-7 100mcg
RECOMMENDED
Doctor's Best, Vitamin K2 MK-7
100 mcg · Morning · ~$16/month

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Best for your goal

Interactions

Other vitamins

Vitamin D3 + K2
Energy · bone · immune
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Baseline nutrition
Methyl-B12
Energy · nerves · cognition
B-Complex
Energy · stress · methylation

Common questions

What is Vitamin K2 MK-7?
Vitamin K2 (menaquinone-7, or MK-7) is the long-acting, animal-derived form of vitamin K that activates two proteins central to calcium routing in the body: osteocalcin, which directs calcium into bone, and matrix Gla protein, which keeps calcium out of arteries. While vitamin K1 (from leafy greens) primarily supports blood clotting, K2 is increasingly recognized as essential for bone density and cardiovascular health. The MK-7 form has a half-life of 72 hours, far longer than MK-4, making once-daily dosing effective. It is especially important to pair with vitamin D3 supplementation. Typical doses are 90-200 mcg per day.
What is Vitamin K2 MK-7 used for?
Bone · arterial calcium routing. Routes calcium into bones and away from arteries. Critical companion when supplementing high-dose vitamin D3.
What is the standard dose of Vitamin K2 MK-7?
100 mcg, typically taken in the morning. Approximate cost is $16 per month.
Who should avoid Vitamin K2 MK-7?
Use extra caution, and speak to a clinician first, if you are on blood thinners.
How strong is the evidence for Vitamin K2 MK-7?
Strong evidence for its primary uses. See the full study list on the research page.

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