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L-Carnosine

Anti-glycation · longevity

Moderate evidence203 studies on PubMedRead the research
Written to our editorial standards · reviewed against published research· Updated 30 May 2026
Last reviewed: May 30, 2026

L-Carnosine: Anti-glycation · longevity. A dipeptide that buffers acid in muscle and shields proteins from glycation, a key driver of aging. Standard dose 500 mg, taken in the morning, about $24/month. Evidence rating: moderate evidence.

Where to buy

NOW Foods L-Carnosine, 500 mg
Recommended
NOW Foods, L-Carnosine
500 mg · Morning · ~$24/month

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NOW Foods L-Carnosine, 500 mgBestseller
L-Carnosine, 500 mg
NOW Foods
100 veg capsules · $22 · ★ 4.7
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NOW Foods L-Carnosine 500 mgBestseller
L-Carnosine 500 mg
NOW Foods
100 veg caps · $24 · ★ 4.7
Buy on iHerb →
Jarrow Formulas L-Carnosine 500 mgPremium
L-Carnosine 500 mg
Jarrow Formulas
90 caps · $26 · ★ 4.7
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Doctor's Best Carnosine 500 mgBest Value
Carnosine 500 mg
Doctor's Best
60 veg caps · $20 · ★ 4.6
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Source Naturals L-CarnosinePremium
L-Carnosine
Source Naturals
60 tablets · $22 · ★ 4.6
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What is L-Carnosine?

Carnosine is a dipeptide of beta-alanine and histidine concentrated in muscle and brain tissue. Its standout property is anti-glycation: it shields proteins from the sugar-driven cross-linking (advanced glycation end-products) that stiffens tissues and accelerates aging. It also buffers acid during intense exercise and acts as an antioxidant in nerve tissue. Levels fall with age and are lower in vegetarians, since the precursors come from meat. Supplemental doses of 500 to 1000 mg daily are studied for healthy aging, skin, and cognition. It is well tolerated, though much is broken down by the enzyme carnosinase, so consistent daily dosing matters.

A dipeptide that buffers acid in muscle and shields proteins from glycation, a key driver of aging.

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Common questions

What is L-Carnosine?
Carnosine is a dipeptide of beta-alanine and histidine concentrated in muscle and brain tissue. Its standout property is anti-glycation: it shields proteins from the sugar-driven cross-linking (advanced glycation end-products) that stiffens tissues and accelerates aging. It also buffers acid during intense exercise and acts as an antioxidant in nerve tissue. Levels fall with age and are lower in vegetarians, since the precursors come from meat. Supplemental doses of 500 to 1000 mg daily are studied for healthy aging, skin, and cognition. It is well tolerated, though much is broken down by the enzyme carnosinase, so consistent daily dosing matters.
What is L-Carnosine used for?
Anti-glycation · longevity. A dipeptide that buffers acid in muscle and shields proteins from glycation, a key driver of aging.
What is the standard dose of L-Carnosine?
500 mg, typically taken in the morning. Approximate cost is $24 per month.
How strong is the evidence for L-Carnosine?
Moderate evidence for its primary uses. See the full study list on the research page.

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