Magnesium L-Threonate
Cognition · sleep depth · brain magnesium
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What is Magnesium L-Threonate?
Magnesium L-Threonate (branded as Magtein) was developed at MIT to address a long-standing problem: most forms of magnesium cannot efficiently cross the blood-brain barrier. Threonate is a unique chelating molecule that shuttles magnesium directly into the central nervous system, raising brain magnesium concentrations in animal and early human studies. Clinical research suggests benefits for working memory, executive function, sleep depth, and age-related cognitive decline. Because the elemental magnesium content per serving is lower than other forms (~144 mg per 2,000 mg dose), it is best used as a brain-focused addition rather than a primary magnesium source.
The only magnesium form clinically shown to raise brain magnesium levels, supports memory, learning, and deep sleep.
Natural food sources
Where possible, get Magnesium L-Threonate from whole foods first. Common dietary sources include:
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