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Tocotrienols (Annatto)

Vitamin E spectrum · skin · liver · cardiovascular

Strong evidenceVegan56 studies on PubMedRead the research
Written to our editorial standards · reviewed against published research· Updated 30 May 2026
Last reviewed: May 30, 2026

Tocotrienols: Vitamin E spectrum · skin · liver · cardiovascular. The often-missing other half of the vitamin E family. Supports skin, lipid profile, liver health, and inflammation. Standard dose 150 mg, taken in the evening, about $38/month. Evidence rating: strong evidence.

Where to buy

Designs for Health Annatto Tocotrienols
Recommended
Designs for Health, Tocotrienols
150 mg · Evening · ~$38/month

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All product options

Designs for Health Annatto TocotrienolsPremium
Annatto Tocotrienols
Designs for Health
60 softgels · $38 · ★ 4.7
Buy on iHerb →
NOW Foods Gamma E TocotrienolsBestseller
Gamma E Tocotrienols
NOW Foods
60 softgels · $24 · ★ 4.6
Buy on iHerb →
Healthy Origins Tocomin TocotrienolsBest Value
Tocomin Tocotrienols
Healthy Origins
60 softgels · $28 · ★ 4.6
Buy on iHerb →
Life Extension Gamma E Tocopherol/TocotrienolsPremium
Gamma E Tocopherol/Tocotrienols
Life Extension
60 softgels · $26 · ★ 4.6
Buy on iHerb →
Swanson TocotrienolsPremium
Tocotrienols
Swanson
60 softgels · $18 · ★ 4.5
Buy on iHerb →

What is Tocotrienols?

Vitamin E exists in eight forms, four tocopherols and four tocotrienols. Most supplements provide only alpha-tocopherol, leaving out the tocotrienols, which have unique benefits not replicable by tocopherols. Annatto-sourced tocotrienols (delta and gamma forms, tocopherol-free) are the most clinically studied. Trials demonstrate benefits for liver enzymes in fatty liver disease, lipid profile, skin UV protection, and bone density. Tocotrienols are also being researched for cancer prevention. Standard dose is 75-300 mg of total tocotrienols per day, with a fat-containing meal.

The often-missing other half of the vitamin E family. Supports skin, lipid profile, liver health, and inflammation.

Natural food sources

Where possible, get Tocotrienols from whole foods first. Common dietary sources include:

Annatto seedsRice branPalm oilOatsBarley

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Common questions

What is Tocotrienols?
Vitamin E exists in eight forms, four tocopherols and four tocotrienols. Most supplements provide only alpha-tocopherol, leaving out the tocotrienols, which have unique benefits not replicable by tocopherols. Annatto-sourced tocotrienols (delta and gamma forms, tocopherol-free) are the most clinically studied. Trials demonstrate benefits for liver enzymes in fatty liver disease, lipid profile, skin UV protection, and bone density. Tocotrienols are also being researched for cancer prevention. Standard dose is 75-300 mg of total tocotrienols per day, with a fat-containing meal.
What is Tocotrienols used for?
Vitamin E spectrum · skin · liver · cardiovascular. The often-missing other half of the vitamin E family. Supports skin, lipid profile, liver health, and inflammation.
What is the standard dose of Tocotrienols?
150 mg, typically taken in the evening. Approximate cost is $38 per month.
How strong is the evidence for Tocotrienols?
Strong evidence for its primary uses. See the full study list on the research page.

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