Does L-Citrulline Malate interact with Beetroot Powder?

Written to our editorial standards · reviewed against published research· Updated 2 Jun 2026
Take together· moderate evidence

Nitric-oxide 'pump' pairing.

Both raise nitric oxide to widen blood vessels and improve blood flow, but by different routes: citrulline converts to arginine to feed the enzyme that makes nitric oxide, while beetroot supplies dietary nitrates the body converts along a separate pathway.

What to do

A common pre-workout 'pump' and endurance stack. Take citrulline (around 6 to 8 g) and beetroot about 1 to 2 hours before training. Beetroot can turn urine or stool pink, which is harmless, and both may slightly lower blood pressure.

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L-Citrulline Malate
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Beetroot Powder
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Common questions

Can I take L-Citrulline Malate and Beetroot Powder together?
Take together. A common pre-workout 'pump' and endurance stack. Take citrulline (around 6 to 8 g) and beetroot about 1 to 2 hours before training. Beetroot can turn urine or stool pink, which is harmless, and both may slightly lower blood pressure.
Why do L-Citrulline Malate and Beetroot Powder interact?
Both raise nitric oxide to widen blood vessels and improve blood flow, but by different routes: citrulline converts to arginine to feed the enzyme that makes nitric oxide, while beetroot supplies dietary nitrates the body converts along a separate pathway.

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Educational use only, not medical advice. Interaction risk depends on dose, your health, and any medications. Always consult a qualified clinician, especially if you take prescription drugs or are pregnant or nursing.