Best time to take Selenium
Written to our editorial standards · reviewed against published research· Updated 2 Jun 2026
Anytime, with food
Take selenium with food; the dose matters more than the time of day.
Selenium supports the thyroid and antioxidant enzymes, but it has a relatively narrow safe range, so the key is dose, not timing. Food reduces any stomach upset.
When
Anytime
With food?
With food
Typical dose
200 mcg
How to take it
Take around 100 to 200 mcg with a meal. A couple of Brazil nuts already supply a day's worth, so do not double up.
Watch out
Do not megadose selenium, too much is toxic.
Full guide
Selenium: benefits, dose & evidence
Read the ingredient guide →Common questions
When is the best time to take Selenium?
Take selenium with food; the dose matters more than the time of day. Take around 100 to 200 mcg with a meal. A couple of Brazil nuts already supply a day's worth, so do not double up.
Should I take Selenium with or without food?
With food. Selenium supports the thyroid and antioxidant enzymes, but it has a relatively narrow safe range, so the key is dose, not timing. Food reduces any stomach upset.
Anything to watch out for with Selenium timing?
Do not megadose selenium, too much is toxic.
Explore further
More timing guides
Selenium interactions
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Take the free quiz →Educational use only, not medical advice. The right timing and dose depend on your health, your other supplements, and any medications. Always consult a qualified clinician, especially if you take prescription drugs or are pregnant or nursing.