Home/Ingredients/Grape Seed Extract

Grape Seed Extract

Vascular · antioxidant · blood pressure

Moderate evidenceVegan568 studies on PubMedRead the research
Written to our editorial standards · reviewed against published research· Updated 30 May 2026
Last reviewed: May 30, 2026

Grape Seed Extract: Vascular · antioxidant · blood pressure. Concentrated OPC antioxidants that support blood vessel health, circulation, and healthy blood pressure. Standard dose 100-300 mg (OPCs), taken in the morning, about $13/month. Evidence rating: moderate evidence.

Where to buy

NOW Foods Grape Seed Extract
Recommended
NOW Foods, Grape Seed Extract
100-300 mg (OPCs) · Morning · ~$13/month

suppdoc.io is an affiliate. Links may earn us a commission at no extra cost to you.

All product options

NOW Foods Grape Seed ExtractBestseller
Grape Seed Extract
NOW Foods
90 veg caps · $13 · ★ 4.7
Buy on iHerb →
Jarrow Formulas Grape Seed ExtractPremium
Grape Seed Extract
Jarrow Formulas
100 veg caps · $16 · ★ 4.7
Buy on iHerb →
Nutricost Grape Seed ExtractBest Value
Grape Seed Extract
Nutricost
240 capsules · $20 · ★ 4.6
Buy on iHerb →
Solgar Grape Seed ExtractPremium
Grape Seed Extract
Solgar
60 veg caps · $14 · ★ 4.6
Buy on iHerb →

What is Grape Seed Extract?

Grape seed extract is a concentrated source of oligomeric proanthocyanidins (OPCs), potent polyphenol antioxidants that protect blood vessels and collagen. Controlled trials show standardized grape seed extract can modestly lower blood pressure, improve circulation and vein health, and reduce oxidative stress, and it is also used for skin and eye support. Effects build over weeks. Standardize to 90 to 95 percent OPCs and dose around 100 to 300 mg daily. It is well tolerated, though like other polyphenols it has mild blood-thinning activity, so pause it before surgery and take care if you use anticoagulants.

Concentrated OPC antioxidants that support blood vessel health, circulation, and healthy blood pressure.

Best for your goal

Other antioxidants

Curcumin (with BioPerine)
Inflammation · joint · recovery
CoQ10 (Ubiquinol)
Cellular energy · heart
Alpha-Lipoic Acid (ALA)
Antioxidant · blood sugar · nerve health
Quercetin (with Bromelain)
Immune · allergies · circulation

Common questions

What is Grape Seed Extract?
Grape seed extract is a concentrated source of oligomeric proanthocyanidins (OPCs), potent polyphenol antioxidants that protect blood vessels and collagen. Controlled trials show standardized grape seed extract can modestly lower blood pressure, improve circulation and vein health, and reduce oxidative stress, and it is also used for skin and eye support. Effects build over weeks. Standardize to 90 to 95 percent OPCs and dose around 100 to 300 mg daily. It is well tolerated, though like other polyphenols it has mild blood-thinning activity, so pause it before surgery and take care if you use anticoagulants.
What is Grape Seed Extract used for?
Vascular · antioxidant · blood pressure. Concentrated OPC antioxidants that support blood vessel health, circulation, and healthy blood pressure.
What is the standard dose of Grape Seed Extract?
100-300 mg (OPCs), typically taken in the morning. Approximate cost is $13 per month.
How strong is the evidence for Grape Seed Extract?
Moderate evidence for its primary uses. See the full study list on the research page.

Not sure if Grape Seed Extract is right for you?

Take our quiz. We'll compose a personalised stack that fits your goals, body, and budget, in minutes.

Take the quiz →