Sulforaphane (Broccoli Sprout)
Detox · longevity · antioxidant
Sulforaphane: Detox · longevity · antioxidant. The most potent natural activator of Nrf2, switching on the body's own antioxidant and detoxification enzymes. Standard dose 10-20 mg (with myrosinase), taken in the morning, about $30/month. Evidence rating: strong evidence.
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What is Sulforaphane?
Sulforaphane is a compound formed when you chew broccoli sprouts, where the precursor glucoraphanin meets the enzyme myrosinase. It is the most potent natural activator of Nrf2, the master switch that turns on hundreds of the body's own antioxidant and detoxification genes. Human trials link sulforaphane to improved clearance of airborne pollutants, better cardiometabolic and inflammatory markers, and promising cognitive effects. Because the enzyme is heat-sensitive, supplements work best when they pair stabilized glucoraphanin with active myrosinase. Three-day-old broccoli sprouts are by far the richest food source.
The most potent natural activator of Nrf2, switching on the body's own antioxidant and detoxification enzymes.
Natural food sources
Where possible, get Sulforaphane from whole foods first. Common dietary sources include:
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