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Niacinamide (B3, Non-Flush)

Skin · NAD+ · joint comfort

STRONG EVIDENCEVEGANREAD THE RESEARCH
Written to our editorial standards · reviewed against published research· Updated 2 Jun 2026
Last reviewed: May 30, 2026
QUICK ANSWER

Niacinamide: Skin · NAD+ · joint comfort. The non-flushing form of B3. Precursor to NAD+ for cellular energy and DNA repair. Topical-quality skin from within. Standard dose 500 mg, taken in the morning, about $11/month. Evidence rating: strong evidence.

What is Niacinamide?

Niacinamide (also called nicotinamide) is the non-flushing form of vitamin B3 and a direct precursor to NAD+, the central coenzyme of cellular energy production and DNA repair. Unlike its cousin niacin, niacinamide does not cause the characteristic skin flush. Clinical research supports niacinamide for skin barrier function, reducing fine lines, supporting joint comfort in mild osteoarthritis, and as adjunctive support during dermatologic treatments. As a NAD+ precursor, it is also studied in the context of cellular aging and longevity research. Standard doses range from 500-1,500 mg per day, typically in divided doses with food.

WHY IT MATTERS

The non-flushing form of B3. Precursor to NAD+ for cellular energy and DNA repair. Topical-quality skin from within.

Natural food sources

Where possible, get Niacinamide from whole foods first. Common dietary sources include:

Chicken & turkeyTunaPeanutsWhole grainsMushrooms

Where to buy

Thorne Niacinamide 500mg
RECOMMENDED
Thorne, Niacinamide
500 mg · Morning · ~$11/month

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Common questions

What is Niacinamide?
Niacinamide (also called nicotinamide) is the non-flushing form of vitamin B3 and a direct precursor to NAD+, the central coenzyme of cellular energy production and DNA repair. Unlike its cousin niacin, niacinamide does not cause the characteristic skin flush. Clinical research supports niacinamide for skin barrier function, reducing fine lines, supporting joint comfort in mild osteoarthritis, and as adjunctive support during dermatologic treatments. As a NAD+ precursor, it is also studied in the context of cellular aging and longevity research. Standard doses range from 500-1,500 mg per day, typically in divided doses with food.
What is Niacinamide used for?
Skin · NAD+ · joint comfort. The non-flushing form of B3. Precursor to NAD+ for cellular energy and DNA repair. Topical-quality skin from within.
What is the standard dose of Niacinamide?
500 mg, typically taken in the morning. Approximate cost is $11 per month.
How strong is the evidence for Niacinamide?
Strong evidence for its primary uses. See the full study list on the research page.

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