Best time to take L-Citrulline Malate

Written to our editorial standards · reviewed against published research· Updated 27 Jun 2026
30 to 60 minutes pre-workout

Take L-citrulline 30 to 60 minutes before training on an empty stomach.

Citrulline raises nitric oxide and blood flow for the session ahead, so it is timed to peak during your workout. An empty stomach speeds absorption.

When
Take pre-workout
With food?
Empty stomach
Typical dose
6 g
How to take it

Take 6 to 8 g of citrulline (or citrulline malate) about 30 to 60 minutes pre-workout.

Watch out

There is little point taking it on non-training days for performance.

Shop L-Citrulline Malate
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Common questions

When is the best time to take L-Citrulline Malate?
Take L-citrulline 30 to 60 minutes before training on an empty stomach. Take 6 to 8 g of citrulline (or citrulline malate) about 30 to 60 minutes pre-workout.
Should I take L-Citrulline Malate with or without food?
Empty stomach. Citrulline raises nitric oxide and blood flow for the session ahead, so it is timed to peak during your workout. An empty stomach speeds absorption.
Anything to watch out for with L-Citrulline Malate timing?
There is little point taking it on non-training days for performance.

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Educational use only, not medical advice. The right timing and dose depend on your health, your other supplements, and any medications. Always consult a qualified clinician, especially if you take prescription drugs or are pregnant or nursing.