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HORMONAL SUPPORT

Chasteberry (Vitex)

PMS · cycle regularity · prolactin balance

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Written to our editorial standards · reviewed against published research· Updated 2 Jun 2026
Last reviewed: May 30, 2026
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Chasteberry: PMS · cycle regularity · prolactin balance. The most-evidenced herb for PMS. Modulates pituitary prolactin and supports luteal phase progesterone. Standard dose 500 mg, taken in the morning, about $22/month. Evidence rating: strong evidence.

What is Chasteberry?

Chasteberry (Vitex agnus-castus), also called monk's pepper, is the most-studied herb for PMS and luteal phase symptoms. It works by binding dopamine D2 receptors in the pituitary, gently lowering prolactin and supporting progesterone in the second half of the menstrual cycle. Multiple randomized trials demonstrate significant reductions in breast tenderness, mood swings, irritability, and bloating across 3+ cycles of use. Effects build slowly, at least 8-12 weeks for full benefit. Standard dose is 20-40 mg of dried fruit equivalent or 200-500 mg of extract, taken in the morning. Avoid during pregnancy or while using hormonal contraceptives.

WHY IT MATTERS

The most-evidenced herb for PMS. Modulates pituitary prolactin and supports luteal phase progesterone.

Where to buy

Gaia Herbs Vitex Berry (Chasteberry)
RECOMMENDED
Gaia Herbs, Chasteberry
500 mg · Morning · ~$22/month

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Common questions

What is Chasteberry?
Chasteberry (Vitex agnus-castus), also called monk's pepper, is the most-studied herb for PMS and luteal phase symptoms. It works by binding dopamine D2 receptors in the pituitary, gently lowering prolactin and supporting progesterone in the second half of the menstrual cycle. Multiple randomized trials demonstrate significant reductions in breast tenderness, mood swings, irritability, and bloating across 3+ cycles of use. Effects build slowly, at least 8-12 weeks for full benefit. Standard dose is 20-40 mg of dried fruit equivalent or 200-500 mg of extract, taken in the morning. Avoid during pregnancy or while using hormonal contraceptives.
What is Chasteberry used for?
PMS · cycle regularity · prolactin balance. The most-evidenced herb for PMS. Modulates pituitary prolactin and supports luteal phase progesterone.
What is the standard dose of Chasteberry?
500 mg, typically taken in the morning. Approximate cost is $22 per month.
Who should avoid Chasteberry?
Use extra caution, and speak to a clinician first, if you are pregnant or nursing.
How strong is the evidence for Chasteberry?
Strong evidence for its primary uses. See the full study list on the research page.

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