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Inositol (Myo + D-Chiro 40:1)

PCOS · hormonal balance · mood

Strong evidenceVegan720 studies on PubMedRead the research
Written to our editorial standards · reviewed against published research· Updated 30 May 2026
Last reviewed: May 30, 2026

Inositol: PCOS · hormonal balance · mood. Vitamin-like compound clinically studied for ovarian function, insulin sensitivity, anxiety, and obsessive thought patterns. Standard dose 2000 mg, taken in the morning, about $22/month. Evidence rating: strong evidence.

Where to buy

Wholesome Story Myo & D-Chiro Inositol 40:1
Recommended
Wholesome Story, Inositol
2000 mg · Morning · ~$22/month

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All product options

Wholesome Story Myo & D-Chiro Inositol 40:1Bestseller
Myo & D-Chiro Inositol 40:1
Wholesome Story
120 capsules · $24 · ★ 4.8
Buy on iHerb →Buy on Amazon →
NOW Foods Inositol PowderBestseller
Inositol Powder
NOW Foods
227 g · $16 · ★ 4.7
Buy on iHerb →
Jarrow Formulas InositolBest Value
Inositol
Jarrow Formulas
100 capsules · $13 · ★ 4.6
Buy on iHerb →
Nutricost Myo-InositolPremium
Myo-Inositol
Nutricost
180 capsules · $15 · ★ 4.6
Buy on iHerb →
Solgar InositolPremium
Inositol
Solgar
100 veg caps · $14 · ★ 4.5
Buy on iHerb →

What is Inositol?

Inositol is a vitamin-like compound that serves as a second messenger for insulin and FSH (follicle-stimulating hormone). The 40:1 ratio of myo-inositol to D-chiro-inositol mirrors the body's natural plasma ratio and is the form used in nearly all published PCOS research. For women with polycystic ovary syndrome, regular supplementation has been shown to support ovulation, menstrual regularity, insulin sensitivity, and androgen balance. Inositol has also been studied at higher doses (12-18 g/day) for anxiety, panic, and obsessive-compulsive symptoms. Standard daily doses are 2-4 g, taken on an empty stomach or with a small meal.

Vitamin-like compound clinically studied for ovarian function, insulin sensitivity, anxiety, and obsessive thought patterns.

Natural food sources

Where possible, get Inositol from whole foods first. Common dietary sources include:

Citrus fruitsCantaloupeBeans & legumesWhole grainsNuts

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Common questions

What is Inositol?
Inositol is a vitamin-like compound that serves as a second messenger for insulin and FSH (follicle-stimulating hormone). The 40:1 ratio of myo-inositol to D-chiro-inositol mirrors the body's natural plasma ratio and is the form used in nearly all published PCOS research. For women with polycystic ovary syndrome, regular supplementation has been shown to support ovulation, menstrual regularity, insulin sensitivity, and androgen balance. Inositol has also been studied at higher doses (12-18 g/day) for anxiety, panic, and obsessive-compulsive symptoms. Standard daily doses are 2-4 g, taken on an empty stomach or with a small meal.
What is Inositol used for?
PCOS · hormonal balance · mood. Vitamin-like compound clinically studied for ovarian function, insulin sensitivity, anxiety, and obsessive thought patterns.
What is the standard dose of Inositol?
2000 mg, typically taken in the morning. Approximate cost is $22 per month.
How strong is the evidence for Inositol?
Strong evidence for its primary uses. See the full study list on the research page.

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