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HORMONAL SUPPORT

Inositol (Myo + D-Chiro 40:1)

PCOS · hormonal balance · mood

STRONG EVIDENCEVEGANREAD THE RESEARCH
Written to our editorial standards · reviewed against published research· Updated 2 Jun 2026
Last reviewed: May 30, 2026
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Inositol: PCOS · hormonal balance · mood. Vitamin-like compound clinically studied for ovarian function, insulin sensitivity, anxiety, and obsessive thought patterns. Standard dose 2000 mg, taken in the morning, about $22/month. Evidence rating: strong evidence.

What is Inositol?

Inositol is a vitamin-like compound that serves as a second messenger for insulin and FSH (follicle-stimulating hormone). The 40:1 ratio of myo-inositol to D-chiro-inositol mirrors the body's natural plasma ratio and is the form used in nearly all published PCOS research. For women with polycystic ovary syndrome, regular supplementation has been shown to support ovulation, menstrual regularity, insulin sensitivity, and androgen balance. Inositol has also been studied at higher doses (12-18 g/day) for anxiety, panic, and obsessive-compulsive symptoms. Standard daily doses are 2-4 g, taken on an empty stomach or with a small meal.

WHY IT MATTERS

Vitamin-like compound clinically studied for ovarian function, insulin sensitivity, anxiety, and obsessive thought patterns.

Natural food sources

Where possible, get Inositol from whole foods first. Common dietary sources include:

Citrus fruitsCantaloupeBeans & legumesWhole grainsNuts

Where to buy

Wholesome Story Myo & D-Chiro Inositol 40:1
RECOMMENDED
Wholesome Story, Inositol
2000 mg · Morning · ~$22/month

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Common questions

What is Inositol?
Inositol is a vitamin-like compound that serves as a second messenger for insulin and FSH (follicle-stimulating hormone). The 40:1 ratio of myo-inositol to D-chiro-inositol mirrors the body's natural plasma ratio and is the form used in nearly all published PCOS research. For women with polycystic ovary syndrome, regular supplementation has been shown to support ovulation, menstrual regularity, insulin sensitivity, and androgen balance. Inositol has also been studied at higher doses (12-18 g/day) for anxiety, panic, and obsessive-compulsive symptoms. Standard daily doses are 2-4 g, taken on an empty stomach or with a small meal.
What is Inositol used for?
PCOS · hormonal balance · mood. Vitamin-like compound clinically studied for ovarian function, insulin sensitivity, anxiety, and obsessive thought patterns.
What is the standard dose of Inositol?
2000 mg, typically taken in the morning. Approximate cost is $22 per month.
How strong is the evidence for Inositol?
Strong evidence for its primary uses. See the full study list on the research page.

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