Best supplements for stress.

Adaptogens and calming nutrients that lower the body's stress response and support a steadier baseline, with the evidence for each.

Written to our editorial standards · reviewed against published research· Updated 2 Jun 2026
Each pick is evidence-graded · we don't sell supplements
  1. 1Omega-3 Fish OilVery strongHigh-EPA fish oil supports cardiovascular health, brain function, mood, and the inflammation curve after training.1250 mg EPA+DHA · morning · ~$22/mo
  2. 2Magnesium GlycinateStrongBioavailable, gentle, non-laxative magnesium. Supports deep sleep, calms the nervous system, eases muscle tension.400 mg elemental · evening · ~$14/mo
  3. 3Ashwagandha KSM-66StrongA clinically-studied adaptogen that lowers cortisol under chronic stress while preserving daytime alertness.600 mg standardised · evening · ~$17/mo
  4. 4Algae Omega-3 EPA/DHAStrongPlant-based EPA/DHA from algae, the same omega-3s as fish oil, since fish get them from algae in the first place.500 mg EPA+DHA · morning · ~$28/mo
  5. 5L-TheanineStrongPromotes alpha brain waves, calm, focused energy without sedation. Pairs beautifully with coffee.200 mg · midday · ~$12/mo
  6. 6B-ComplexStrongMethylated B-vitamins support energy metabolism, stress response, and methylation pathways.1 capsule (active forms) · morning · ~$22/mo
  7. 7InositolStrongVitamin-like compound clinically studied for ovarian function, insulin sensitivity, anxiety, and obsessive thought patterns.2000 mg · morning · ~$22/mo
  8. 8Magnesium CitrateStrongHigher-absorption, mildly laxative form of magnesium. A solid daily option when bowel regularity is also a goal.400 mg elemental · evening · ~$11/mo
  9. 9Bacopa MonnieriStrongAyurvedic herb with consistent evidence for memory consolidation and learning, but effects build slowly (8-12 weeks).750 mg standardised · morning · ~$13/mo
  10. 10MethylfolateStrongThe bioactive form of folate, bypasses the MTHFR enzyme, supporting methylation, mood, and homocysteine balance.1 mg · morning · ~$16/mo
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Common questions

What is the best supplement for stress?
Ashwagandha has the strongest evidence for lowering cortisol and perceived stress; L-theanine and magnesium glycinate help with in-the-moment calm and relaxation.
How long do stress supplements take to work?
L-theanine and magnesium can feel calming within an hour; adaptogens like ashwagandha usually take 2-4 weeks of daily use to show their full effect.

Educational use only, not medical advice. Always consult a qualified clinician before starting supplements, especially if you take medication or are pregnant or nursing.