Folate: what it means.
B-vitamin needed for DNA synthesis and methylation.
Written to our editorial standards · reviewed against published research· Updated 2 Jun 2026
Typical reference bands (ng/mL)
Lowunder 4 ng/mL
Optimal7-20 ng/mL
Ranges vary by laboratory, age, and sex, your lab's own reference range always takes precedence.
Common causes
- Low intake of leafy greens and legumes
- Regular alcohol use
- Pregnancy, which raises demand
- MTHFR variants that slow activation of folic acid
What it can feel like
- Fatigue
- Mouth sores
- Low mood
- In pregnancy, a higher neural-tube-defect risk
Who should test
Relevant before and during pregnancy, with heavy alcohol use, or alongside an elevated homocysteine.
Supplements that help raise Folate
Evidence-led, and only a piece of the picture, diet, lifestyle, and your clinician matter most.
Methylfolate is the active form the body uses directly, useful for those with MTHFR variants who convert folic acid poorly.
See your own Folate
Upload your blood test, we read folate and your other markers, then match evidence-led supplements.
Analyze my bloodwork →Explore further
Research-backed stacks
Related biomarkers
Common questions
What does a low Folate mean?
Common drivers include low intake of leafy greens and legumes; regular alcohol use; pregnancy, which raises demand. A result outside the optimal range is best read in context: discuss it with your clinician, who can weigh the full picture and your lab's own reference range.
What supplements help raise Folate?
Evidence-led options include Methylfolate, B-Complex. They support, but don't replace, diet, lifestyle, and medical care.
Educational use only, not medical advice or diagnosis. Always interpret lab results with a qualified clinician.