Vitamin B6: what it means.
Cofactor for neurotransmitter synthesis and homocysteine clearance.
Written to our editorial standards · reviewed against published research· Updated 2 Jun 2026
Typical reference bands (µg/L)
Lowunder 5 µg/L
Optimal10-50 µg/L
Ranges vary by laboratory, age, and sex, your lab's own reference range always takes precedence.
Common causes
- Low intake
- Regular alcohol use
- Certain medications
- Malabsorption
What it can feel like
- Low mood or irritability
- Tingling in the hands or feet
- Cracked lips or a sore tongue
Who should test
Relevant alongside an elevated homocysteine or neurological symptoms. Note that very high, long-term B6 can itself cause nerve symptoms, so dosing matters.
Supplements that help raise Vitamin B6
Evidence-led, and only a piece of the picture, diet, lifestyle, and your clinician matter most.
B6 (as P5P, often in a B-complex) is a cofactor for neurotransmitter production and, with folate and B12, for clearing homocysteine.
See your own Vitamin B6
Upload your blood test, we read vitamin b6 and your other markers, then match evidence-led supplements.
Analyze my bloodwork →Explore further
Research-backed stacks
Related biomarkers
Common questions
What does a low Vitamin B6 mean?
Common drivers include low intake; regular alcohol use; certain medications. A result outside the optimal range is best read in context: discuss it with your clinician, who can weigh the full picture and your lab's own reference range.
What supplements help raise Vitamin B6?
Evidence-led options include Vitamin B6, B-Complex. They support, but don't replace, diet, lifestyle, and medical care.
Educational use only, not medical advice or diagnosis. Always interpret lab results with a qualified clinician.