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GUT & DIGESTIVE

DGL Licorice

Stomach lining · heartburn · gut comfort

MODERATE EVIDENCEVEGANREAD THE RESEARCH
Written to our editorial standards · reviewed against published research· Updated 2 Jun 2026
Last reviewed: May 30, 2026
QUICK ANSWER

DGL Licorice: Stomach lining · heartburn · gut comfort. Deglycyrrhizinated licorice, soothes the stomach lining without the blood-pressure effect of regular licorice. Standard dose 400 mg, taken in the morning, about $14/month. Evidence rating: moderate evidence.

What is DGL Licorice?

Deglycyrrhizinated licorice (DGL) has the glycyrrhizin removed, the compound responsible for licorice's potential to raise blood pressure, while retaining the flavonoids that soothe and protect the gastric mucosa. DGL stimulates mucus secretion, supports the production of new stomach lining cells, and has been used clinically for heartburn, gastritis, and mild peptic ulcer for decades. It's commonly chewed before meals to coat the esophagus and stomach. Standard dose is 400-800 mg, 20 minutes before meals. Safer than regular licorice for long-term use, but pregnant women should still consult a clinician.

WHY IT MATTERS

Deglycyrrhizinated licorice, soothes the stomach lining without the blood-pressure effect of regular licorice.

Where to buy

Now Foods DGL Licorice 400mg
RECOMMENDED
Now Foods, DGL Licorice
400 mg · Morning · ~$14/month

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Stacks that include DGL Licorice

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The Gut Reset Stack
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Common questions

What is DGL Licorice?
Deglycyrrhizinated licorice (DGL) has the glycyrrhizin removed, the compound responsible for licorice's potential to raise blood pressure, while retaining the flavonoids that soothe and protect the gastric mucosa. DGL stimulates mucus secretion, supports the production of new stomach lining cells, and has been used clinically for heartburn, gastritis, and mild peptic ulcer for decades. It's commonly chewed before meals to coat the esophagus and stomach. Standard dose is 400-800 mg, 20 minutes before meals. Safer than regular licorice for long-term use, but pregnant women should still consult a clinician.
What is DGL Licorice used for?
Stomach lining · heartburn · gut comfort. Deglycyrrhizinated licorice, soothes the stomach lining without the blood-pressure effect of regular licorice.
What is the standard dose of DGL Licorice?
400 mg, typically taken in the morning. Approximate cost is $14 per month.
How strong is the evidence for DGL Licorice?
Moderate evidence for its primary uses. See the full study list on the research page.

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